After a crane collapse buries a woman (China Shavers) beneath rubble, House must split his time between staying with her and diagnosing the crane operator (Doug Kruse) who passed out. But when she dies despite his best efforts, House must avoid the temptation to relapse on Vicodin — until Cuddy admits her love for him.





House tells Dr. Nolan about the case of a woman (Zoe McLellan) suffering from both amnesia and another mystery condition. But Dr. Nolan believes that something else is troubling House — including the fact that Wilson is kicking him out of their home.





The team takes on the case of an ailing groom-to-be who harbors undisclosed secrets from a previous relationship. As his fiancée tries to get answers to her many questions, a frustrated team winnows down the possibilities. Meanwhile, House spends extra-curricular time with his Princeton Plainsboro colleagues, performing a karaoke rendition of a Gladys Knight & The Pips classic with Foreman and Chase.





A woman in an open marriage suddenly becomes ill during a date with her boyfriend; House tests Wilson and Sam’s relationship.





House and the team take on the case of Sir William, a “knight” in a closed-off community of men and women living according to the ideals of the High Renaissance. As the team searches the medieval village for environmental factors contributing to Sir William’s rapidly deteriorating health, Thirteen and Sir William debate the acts that define honor and loyalty, especially in regard to the “queen” of the community, one of Sir William’s most frequent visitors. Meanwhile, Wilson starts over with an ex.





When the hospital is sent into lockdown mode due to a missing infant, all of the doctors must remain where they are, leaving Foreman and Taub in the file room, Wilson and Thirteen in the cafeteria playing truth or dare, House in a room with a patient (David Strathairn), and Chase with his ex-wife, Cameron, as Cuddy tries to help police locate the infant.





The team takes on the case of a high school senior who inexplicably blacks out during a class field trip. While in the hospital, the patient repeatedly hallucinates. After exhausting myriad ineffective treatments for her mysterious ailments, House attempts one last controversial approach to diagnosing her: monitoring her cognitive patterns and looking for clues. Meanwhile, Taub airs his dirty laundry at work, and Wilson attempts to furnish his condo.





The team treats a famous blogger, but finds her difficult to treat when she insists on discussing all procedures and doctors on her blog. Meanwhile, House and Wilson learn secrets about each other and go speed dating along with Chase.





During a day in the life of Princeton Plainsboro’s Dean of Medicine, Dr. Lisa Cuddy, the inner workings of the hospital are seen through her eyes. This day proves to be especially trying as Cuddy wrestles with myriad hospital issues and staff disputes that test her perseverance and skills as an administrator, all while juggling issues in her personal life.





House and the team rush to treat an ailing college football star in time for the patient to compete in NFL tryouts. But when the patient experiences an onslaught of varied and unusual symptoms, the team has trouble reaching a consensus on how to effectively treat him in time. Meanwhile, Foreman’s brother Marcus (guest star Jones) makes a surprise visit to the hospital.